This delicious, hearty chicken casserole is the perfect low-carb comfort food! Packed with tender chicken, wholesome vegetables, creamy sauce, and cheesy goodness, it’s great for family dinners, meal prep, or anyone following a keto or low-carb lifestyle. You’ll love how quickly it comes together and how satisfying it is—without any guilt! 😋✨

📋 Ingredients
- 3 cups shredded cooked chicken breast
- 2 cups broccoli florets, chopped
- ½ cup red bell pepper, diced
- ½ cup mushrooms, sliced
- ½ cup sour cream
- ½ cup mayonnaise
- ½ cup heavy cream
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1 teaspoon paprika
- Salt and pepper to taste
- 1½ cups shredded cheddar cheese
🔄 Substitutions
- Chicken: Use cooked turkey breast, rotisserie chicken, or even ground turkey as alternatives.
- Vegetables: Substitute broccoli with cauliflower, zucchini, spinach, or asparagus.
- Cheese: Swap cheddar for mozzarella, Swiss, Monterey Jack, or Pepper Jack.
- Heavy Cream: Replace with coconut cream for dairy-free diets.
👩🍳 How to Make
Step 1: Prepare Oven
Preheat oven to 375°F (190°C). Lightly grease a casserole dish.
Step 2: Combine Ingredients
In a bowl, mix chicken, broccoli, peppers, mushrooms, sour cream, mayonnaise, heavy cream, garlic powder, onion powder, paprika, salt, pepper, and 1 cup of shredded cheese. Stir until well combined.
Step 3: Bake
Spread evenly into the casserole dish. Top with the remaining ½ cup shredded cheddar cheese. Bake uncovered for 25–30 minutes until golden and bubbling.
Step 4: Serve
Allow to rest for 5 minutes, garnish with parsley or green onions, and enjoy!

🥦 Mix-ins (Optional)
- Cooked bacon bits
- Sliced jalapeños (for spice)
- Green onions or chives
- Fresh herbs (thyme, basil, or oregano)
✅ Recipe Tips
- Use rotisserie chicken or leftover cooked chicken for convenience.
- Freshly shredded cheese melts better and tastes richer than pre-packaged shredded cheese.
- Slightly steam or sauté vegetables first for tender results.
📦 Storage
- Refrigerator: Store leftovers covered or in airtight containers for up to 4 days.
- Freezer: Freeze in airtight containers or freezer bags for up to 3 months. Thaw overnight in the refrigerator before reheating.
🍽️ Recipe Variations
- Mexican-Inspired: Add salsa, cumin, and taco seasoning; top with avocado slices.
- Italian Twist: Add basil pesto, mozzarella cheese, and sun-dried tomatoes.
- Buffalo Chicken: Mix in buffalo sauce, blue cheese crumbles, and celery.
❓ FAQs
Can I use frozen vegetables?
Yes, but thaw and drain excess moisture before adding to avoid a watery casserole.
Can this be made ahead of time?
Absolutely! Assemble the casserole and refrigerate up to 24 hours before baking. Add 5 extra minutes to baking time if chilled.
How to reheat leftovers?
Reheat in the oven at 350°F (175°C) until warmed through (about 15–20 minutes), or microwave until hot.
Enjoy this tasty, wholesome chicken casserole—perfect for easy low-carb dinners! 🍗🥦✨

Ava Brooks is the home cook behind RecipeSharingHub, sharing dependable, step‑by‑step recipes for busy weeknights and easy weekend bakes. When not testing dishes, Ava snaps kitchen photos and answers reader questions in the comments. Discover the latest recipes or join the newsletter for new ideas each week.